Cefotaxim sodium equivalent to ……………………1g cefotaxim.
Each solvent ampoule contains:
Sterile water for injection q.s to ……………….….. 4ml
Powder for injection.
Box of 1 vial and 1 solvent ampoule
Box of 10 vials
Cefotaxime is indicated for the treatment of patients with serious infections such as: lower respiratory tract infections, genitourinary infections, gynecologic infections, septicemia, skin and skin structure infections, intra-abdomical infections, bone and joint infections and central nervous system infections. It is also used for prevention and treatment of surgical operations.
Warnings and cautions when taking drugs
Do not store above 25°C. Protect from light and moisture.
Dosage and Administration
Cefotaxime is administered by IV injection over 3 to 5 minutes or infusion or by deep IM injection.
Dosage and type of administration depend on the severity of the infection, the sensitivity of the bacterium and the condition of the patient.
– Adults and children over 12 years in general are given 2-6 g a day in 2-3 divided doses. In severe cases, the daily dose can be increased up to 12 g in 3-6 divided doses.
For the treatment of gonorrhoea in adults, a single dose of 1g cefotaxime is used.
– Infants and children up to 12 years old:
The usual daily dose is 100 to 150 mg/kilogram bodyweight/day. This is usually split into 2 doses each day. Severely ill children may receive up to 200 mg/kg bodyweight daily (to a maximum of 6 g daily), split into 3 separate doses.
Renal impairment and geriatric patients:
Dose reduction is necessary
Perioperative infection prophylaxis
For peri-operative infection prophylaxis, the administration of a single dose of 1g cefotaxime 30 to 60 minutes prior to the operation is recommended.