Each Film-coated tablet contains:
Lamivudine ……………………………………100mg
Excipients q.s to…………………………….a tablet
Film-coated tablets
Box of 1 blister x 10 tablets
Box of 3 blisters x 10 tablets
– Bilavir is indicated for the treatment of chronic hepatitis B in adult with
+ Compensated liver disease with evidence of active viral replication, persistently elevated serum alanine aminotransferase (ALT) levels and histological evidence of active liver inflammation and/ or fibrosis.
+ Decompensated disease
– Treat HIV infection in combination with other medicines.
Not exceeding 30°C, dry place away from light.
Lamivudin should be used in combination with other medications (Zidovudin or Stavudin)
– ADULTS: 300 mg once daily.
– CHILDREN: 3 months to 12 year old: 4 mg/kg twice daily, maximum dose of 300 mg daily.
– ADULTS: 100 mg x 1 time per day
– CHILDREN (over 2 year old): 3 mg/kg two times per day (maximum 100 mg/day). Safety and efficacy of treatment older than 1 yr not established.
Dosage adjustments in renal impairment:
Creatinine clearance (ml/minute) | Dosage of Lamivudine ( >16 years ) |
≥50 | 150 mg twice daily |
30 – 49 | 150 mg once daily |
15 – 29 | 150 mg first dose, then 100 mg once daily |
5 – 14 | 150 mg first dose, then 50 mg once daily |
< 5 | 50 mg first dose, then 25 mg once/day |
Please read carefully the leaflet before using.
